Pharmaceutical preparations and substances for the treatment of peripheral nerve pain and nitric oxide insufficiency associated with diabetes, trauma, auto- immune diseases, vasculopathies, infections, venous insufficiency, nutrient deficiencies and chemical insult; Medicated topical skin preparations for the treatment of nerve pain; Topical creams containing plant derived nitrates, nitrites, and polyphenols for improving and reducing peripheral nerve pain; Topical pharmaceutical skin creams containing plant derived nitrates, nitrites, and polyphenols for improving and reducing peripheral nerve pain; Pharmaceutical preparations for the relief of pain; Pharmaceutical preparations for the treatment of pain; Herbal topical creams, gels, sprays, balms, liniment and ointments for the relief of pain