Laboratory instruments, devices, equipment, namely, systems incorporating a laser for illumination of pathogenic cellular analytes in a fluid, a flow system for channeling pathologic cellular analytes in a fluid through a detection chamber, and a sensitive sound detection system for identification of acoustic signals derived from specific pathologic cellular analytes illuminated by laser light as they pass through a detection chamber, and downloadable software for the detection, enumeration, analysis, characterization and capture of circulating tumor cells and pathogens, namely, bacteria, fungi, parasites and viruses, for scientific, laboratory and general research uses; laboratory instruments, devices and equipment, namely, systems incorporating a laser for illumination of pathogenic cellular analytes in a fluid, a flow system for channeling pathologic cellular analytes in a fluid through a detection chamber, and a sensitive sound detection system for identification of acoustic signals derived from specific pathologic cellular analytes illuminated by laser light as they pass through a detection chamber, for use in the environmental monitoring of seawater and fresh water for biological and pathogenic organisms