Medical instruments and systems used to decontaminate surfaces of various medical devices and containers, namely vial, a bag, a bottle, a syringe, an infusion line, a connector, a filter, a manifold, a container port, a bag port, a bottle port, a vial port; medical instruments and systems to displace air-particles while forming a hermetically sealed connection between medical devices namely, a vial, a bag, a bottle, a syringe, an infusion line, a connector, a filter, a manifold, a container port, a bag port, a bottle port, a vial port; medical instruments and systems that externally displace, internally displace, slide, and reseal while maintaining a hermetically sealed connection while maintaining sterility and removing air particles namely vial, a bag, a bottle, a syringe, an infusion line, a connector, a filter, a manifold, a container port, a bag port, a bottle port, a vial port