Computer-based apparatus and computer systems for detection and analysis of biomolecules for scientific use; computer-based apparatus and computer systems for scientific research, namely, for detecting, collecting and processing optical signals and images, into data for use in the analysis of biomolecules in connection with scientific or medical research; computer-based apparatus and computer systems for detection and analysis of gene expression, nucleic acid sequencing, RNA transcription and microRNA expression profiling, proteomics, single nucleotide polymorphisms analysis, nucleic acid sequencing, detection of polymorphisms, detection of copy number variations, analysis of functional pathway gene sets, and prognostic, predictive, clinical, oncology, and hematology diagnostics; laboratory equipment for sample preparation, mixing, hybridization, incubation, washing, identifying the location and imaging of single molecule reporters namely, fluid mixers, positive displacement pumps for fluid transport and metering, directional control and flow control valves for fluid regulation, dispensing and metering, hybridization ovens and containers, reagent holders, sample containers and microfluidic devices comprising microfluidic and nanofluidic channels formed on or in a substrate for the transport and analysis of fluid samples, scanning microscopes, fluorescent microscopes, electromagnetic sensors and replacement parts therefor in the fields of scientific research; computer systems, namely, computer software and downloadable electronic data files used to acquire, analyze, manage and report biological information; kits for scientific research use, namely, for use in detecting the presence of analytes in samples, identifying sample type and nucleic acid sequencing, comprised primarily of microfluidic devices comprising microfluidic and nanofluidic channels formed on or in a substrate for the transport and analysis of fluid samples, oligonucleotides, buffers, labels, and substrates, containers, dishes, microscope slides, plastic bags, swabs, test tubes, vials and wipes; diagnostic test kits for scientific use comprising microscope slides, microfluidic devices comprising microfluidic and nanofluidic channels formed on or in a substrate for the transport and analysis of fluid samples, reports, test results, research material, worksheets and other non-printed documents and publications in the field of scientific research, all being downloadable