Ingestible medications and pharmaceutical preparations, both prescription and over-the-counter, and placebo pill preparations for medical use containing an ingestible sensor for use in connection with humans and animals to facilitate in the provision of data related to the patient including patient physiologic data, patient environment, treatment data, data related to medications, pharmaceuticals, and supplements, and data transmitted by medical devices for the purpose of maximizing patient outcome in the diagnosis, treatment, and management of cancers, chronic pain, skin disease, diseases of the ear, nose, and throat, infectious diseases, psychiatric disorders, and diseases of the cardiovascular, respiratory, metabolic, immune, central nervous, endocrine, glandular, musculoskeletal, digestive, excretory, and reproductive systems; dietary and nutritional supplements containing an ingestible sensor for use in connection with humans and animals to facilitate in the provision of data related to the patient, patient environment and the supplement