Custom cell-line engineering services; scientific research in the field of genetics and genetic engineering, namely, gene-editing services, DNA modelling services, gene engineering services, establishing patient genotypes; bio-technology, pharmaceutical and scientific testing, research, development, advice, consultancy and information services; biological research; pharmaceutical research services; drug discovery services; research and development services for lead identification and validation; research and development services for target identification and validation; pharmaceutical research, namely, identification of patient-relevant drug targets, optimisation of drug candidates for clinical development; diagnostic services; medicinal research services, namely, hit discovery and hit to lead services; research and development services in the nature of creating libraries and collections of cells and cell lines, chemicals and compounds; research and development services in the nature of creating libraries and collections of normal and mutated genes; research and development services relating to targeting therapies to individuals; research and development services relating to combining therapies for individuals; research and development relating to reagents; scientific research in the field of disease modelling; medical and scientific research, namely, designing and conducting clinical trials for others; research and development in re-positioning existing drugs from other therapeutic indications