Computer hardware and communications server hardware and software for use in sensing and monitoring health and wellness; computer software used for drug safety management, namely, management and declaration of adverse event reactions including tracking and reporting safety issues related to the clinical trials for life science companies; computer software used for managing the data entry of safety issues, create a workflow to assist users in handling the issues, reference a product's overall safety from statistical, bureaucratic, and research perspective, and track all data; computer software used in the management of clinical trials of pharmaceutical products and medical devices and management of data resulting there from; computer software for medical and hospital business office administration and information management, including electronic and paper billing, patient information storage and retrieval, appointments management, insurance claim preparation and electronic submission, payment tracking and payment comparisons, management of medical and hospital data for regulatory compliance, managing managed care and capitation contracts with payor analysis, batch payment processing, collections, and referral authorization