pharmaceutical compositions, namely, preparations for the treatment of cancer, diabetes, neurodegenerative disorders, cardiovascular disease and disorders, metabolic syndrome, autoimmune disorders, central nervous system diseases and disorders, neurological disorders, urological disorders, gastrointestinal disorders, musculoskeletal disorders, allergies, hypertension, erectile dysfunction, sexual dysfunction, stroke, migraines, pain, inflammation and inflammatory diseases, respiratory and infectious diseases, immunological disorders, anxiety, depression, neuropsychiatric disorders including both psychotic and non-psychotic conditions, and substance abuse disorders, including both abuse and dependence, disorders of blood cell production, organ transplant rejection, endocrinologic disorders, and bacterial, viral and fungal diseases; diagnostic products, namely, medical diagnostic reagents, diagnostic reagents for clinical or medical laboratory use; biological reagents for medical purposes in the field of molecular biology; and reagents for use in biological processing for medical purposes