Pharmaceutical and medicinal preparations and substances for the treatment of metabolic disorders, hormone deficiencies, skin diseases, skin disorders, bone diseases, bone disorders, sexually transmitted diseases, diseases of the central nervous system, cancer, microbial conditions and infections, rectal conditions, rectal diseases and rectal disorders, vitamin and mineral deficiencies, pain, gastro-intestinal conditions, and cardiovascular conditions; pharmaceutical preparations, substances and gels for hormone replacement; sanitary preparations for medical use; dietetic foods and dietetic food supplements adapted for medical use; medical plasters; materials for dressings, namely, burn dressings, surgical dressings, and wound dressings; gauzes and bandages for dressings; transdermal patches containing pharmaceutical preparation for the treatment of metabolic disorders, hormone deficiencies, skin diseases, skin disorders, bone diseases, bone disorders, sexually transmitted diseases, diseases of the central nervous system, cancer, microbial conditions and infections, rectal conditions, rectal diseases and rectal disorders, vitamin and mineral deficiencies, pain, gastro-intestinal conditions, and cardiovascular conditions; transdermal gel for hormone therapy; testosterone gel; hormone preparations for the treatment of hypogonadism; pharmaceutical preparations for the treatment of diabetes, insulin resistance and metabolic syndrome